The Evaluation of Traditional Medicine to Cure Sickle Cell Anaemia: A Review Evaluation of traditional medicine to cure sickle cell anaemia: A Review
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Sickle cell disorder, traditional medicines, medicinal plants, anti-sickling agents, Zanthoxylum chalybeum, Cajanus cajan, Carica papaya
Abstract
According to this assessment, medicinal plants have shown to be an invaluable tool in the treatment of a wide range of illnesses in underdeveloped nations, including sickle cell disease. Due to cultural choices and the high expense of conventional treatment, many people in both industrialised and developing nations rely significantly on traditional medicine. The bioactive compounds responsible for the therapeutic effects of these plants are often unidentified, and traditional healers emphasise a holistic approach in their treatments. These therapeutic compounds are referred to as the "active principles" of the plants. In the context of sickle cell anaemia, herbal medicine plays a crucial role. Research indicates that while the gene causing the disease is dominant and highly expressive, males are more affected than females, whereas females usually act as carriers because the gene is recessive. Numerous plants with immunomodulatory effects have been reported in the literature, and some of these have been validated through the use of contemporary scientific techniques. The usefulness of several phytomaterials in treating sickle cell disease has been documented. These include of Zanthoxylum Chalybeum, Cajanus cajan, Garcinia kola Heckel, Carica papaya, Scoparia dulcis, etc. and *Aloe vera* can reduce sickling in vitro and lengthen the gelling period of sickle cell blood. These findings indicated that these plants have a great deal of possibilities for treating sickle cell diseases
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