The Antibacterial, Antioxidant Properties and Natural Compound Screening Method of Cinnamomum zeylanicum Bark was Investigated through FTIR Testing
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Abstract
Both in vivo and in vitro studies have demonstrated that phytochemical components of photobiotic have potent antibacterial effects against Gram-positive and Gram-negative bacteria. There was a lack of data on cinnamon powder's minimum inhibitory concentration (MIC) and in vitro antibacterial effectiveness against different microorganisms. Thus, the purpose of this research was to compare the in vitro antibacterial activity and MIC of cinnamon powder extracts with that of conventional antibacterial medications against a range of microorganisms. The standards of CTX-Cefotaxime and GN-Gentamicin, as well as the methanolic crude extract and ethanol fraction of Cinnamomum zeylanicum bark extracts, have antibacterial activities that were measured at 21.08±0.33, 16.89±0.31, 34.00±0.32, and 29.60±0.31 respectively for Bacillus subtilis, and recorded 13.89±0.29, 17.00 ±0.32, 24.81±0.25, and 26.90±0.27 respectively for Enterococcus faecalis, while recorded 09.11±0.15, 19.75±0.32, 20.00±0.21 and 17.45±0.19 respectively for Streptococcus pyogenes, in the same time antibacterial activity recorded 15.00±0.30, 08.68±0.14, 27.90±0.29 and 26.04±0.29 respectively for Staphylococcus epidermidis and recorded 15.90±0.30, 14.06±0.29, 29.95±0.31 and 32.17±0.33 respectively for Staphylococcus aureus. FT-IR peak values of solid analysis of Cinnamomum zeylanicum Bark. Peak (Wave cm-ˡ, Intensity, Corr. Intensity, Base (H), Area, Bond, Type of Vibration, and Functional group assignment recorded 667.37, 70.282, 2.383, 667.01, 2.226 and Alkenes; 690.52, 71.720, 0.518, 713.66, 3.769, and Alkenes; 788.89, 77.439, 2.341, 821.68, 4.707, Alkenes; 999.13, 66.259, 1.402, 1006.84, 12.823, and Alkenes; 1029.99, 63.849, 0.209, 1031.92, 4.297, and alkyl halides; 1226.73, 82.894, 0.214, 1228.66, 2.659, and alkyl halides; 1417.68, 85.533, 0.939, 1427.32, 2.347, and alkyl halides; 1454.33, 85.135, 1.371, 1483.26, 2.052, and alkyl halides; 1516.05, 85.999, 0.843, 1521.84, 1.943, and Aromatic; 1539.20, 85.109, 1.482, 1571.99, 2.655, and Aromatic; 1645.28, 78.585, 0.511, 1647.21, 5.122, Amide; 2854.65, 85.991, 4.453, 2868.15, 2.326, and Alkane. The anti-oxidant properties of Cinnamomum zeylanicum were studied in methanol, ethanol extract, and standards, specifically looking at its ability to scavenge superoxide and nitric oxide radicals recorded 23.79±1.92, 19.84±1.75, and Quercetin (standard) 41.00±3.07 respectively of Superoxide radical scavenging. 43.90±3.08, 31.00±2.95, and Curcumin (standard) 65.00±4.97 respectively of Nitric oxide radical scavenging.
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