Journal of Current Medical Research and Opinion http://www.cmro.in/index.php/jcmro <p><em><strong>Journal of Current Medical Research and Opinion</strong> </em>is a peer-reviewed, international journal for the rapid publication of original research on new and existing drugs and therapies, and post-marketing investigations. Equivalence, safety and efficacy/effectiveness studies are especially encouraged. </p> <p>The aim of <em><strong>Journal of Current Medical Research and Opinion</strong> </em>is to provide ethical, unbiased and rapid publication of quality content that is validated by rigorous peer review. Journal aim is to serve the information needs of the clinical medicine community, to help translate medical advances into patient care and be a leader in transparency/disclosure by facilitating a collaborative and honest approach to publication.</p> <h2>Aims and scope:</h2> <p><em>CMRO</em> is the flagship medical journal. An open access, open peer-reviewed general medical journal, <em>CMRO</em> outstanding and influential research in all areas of clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. We also publish stimulating debates and reviews as well as unique forum articles and concise tutorials. </p> en-US editor@cmro.in (Edwin Jarald) daga@cmro.in (Gaurav Daga) Fri, 08 Aug 2025 19:11:03 +0000 OJS 3.3.0.15 http://blogs.law.harvard.edu/tech/rss 60 MMA Incidence of surgical site infection following caesarean section and its associated factors in a Tikrit Teaching Hospital, Iraq http://www.cmro.in/index.php/jcmro/article/view/1085 <p><strong>Objective</strong></p> <p><strong>&nbsp;</strong>The rate of delivery by caesarean section has increased greatly. This increase has been attributed to wide variety of factors related to mother, child, medical and legal climate. Post-operative caesarean section infection is an important of maternal febrile morbidity. It leads to prolongation of hospital stay and add extra cost to patient charge for hospitalization.</p> <p><strong>Materials and Methods</strong></p> <p><strong>&nbsp;</strong>The present work was conducted on 500 patients with caesarean sections.. Their ages ranged from 15-45 years. The majority of these patients were from rural areas or referred to this hospital from other town’s hospitals. General information such as including demographic survey was listed. Wound infection was assessed by culture.</p> <p>&nbsp;&nbsp;<strong>Results</strong></p> <p><strong>&nbsp;</strong>&nbsp;Caesarean wound infections ranged from grade 0 to grade 5c. The highest percentage ( 48.8 ) of wounds was of grade 0. The high incidence of caesarean infection was among the age group 21-30 years old. The present study showed that 46.7% of patients with body weight more than 85 kgs developed wound infection. The present study revealed that 62.4% of patients come from rural areas. Wound infection rates for elective, emergency and caesarean after trail were 13.6, 18.5 and 22.4 percent respectively.</p> <p>&nbsp;<strong>Conclusions</strong></p> <p>&nbsp;Chi-squared test showed a significant difference strong association between weight group and infection rate ( P ˂ 0.00001). On bacteriological examination of caesarean wounds, grade 4, 5s and grade 5c showed 100% positive bacterial cultures. The <strong>present attempt</strong> showed that the pooled infection rate was 18.4% with 95% confidence limits.</p> Mohemid Al-Jebouri, Hana Salman Al-Bayati Copyright (c) 2025 Journal of Current Medical Research and Opinion https://creativecommons.org/licenses/by/4.0/ http://www.cmro.in/index.php/jcmro/article/view/1085 Thu, 14 Aug 2025 00:00:00 +0000 The Analysıs of Endometrıal Samplıng on Results Reported as Insuffıcıent Samples http://www.cmro.in/index.php/jcmro/article/view/1088 <p><strong>OBJECTIVE</strong></p> <p>The aim of this study is to evaluate the pathology results of second endometrial samplings performed in cases where the initial endometrial sampling was reported as insufficient material by the pathology unit.</p> <p><strong>MATERIAL METHOD</strong></p> <p>This study analyzed the results of 6,612 patients who underwent endometrial sampling at Prof. Dr. Cemil Taşçıoğlu City Hospital between 2019 and 2023, using the hospital's electronic record system. Data from 615 patients whose samples were reported as insufficient and 257 patients who underwent repeat procedures were included in the study. Patients were evaluated based on age, parity, menopausal status, indication for endometrial sampling, endometrial thickness, and the type of anesthesia used.</p> <p> </p> <p><strong>STATİSTİCAL METHOD</strong></p> <p>For statistical analysis, SPSS 15.0 for Windows was used. Descriptive statistics were presented as numbers and percentages for categorical variables, and as mean, standard deviation, minimum, maximum, and median for numerical variables. Since the assumption of normal distribution was not met, comparisons of numerical variables between more than two independent groups were performed using the Kruskal-Wallis test, while comparisons between two groups were conducted using the Mann-Whitney U test. Subgroup analyses were interpreted using Bonferroni correction. Proportions between groups were compared using the Chi-square test. A significance level of p&lt;0.05 was considered statistically significant.</p> <p><strong>FINDINGS</strong></p> <p>The files of 6612 patients were reviewed. Pathology results of 615 (9.3%) of these patients were evaluated as inadequate specimens. According to hospital data, 257 of these 615 patients underwent repeat endometrial biopsy, 105 (40.8%) of whom had an unsatisfactory result. Of the 152 patients with an adequate sample, atrophy (34.2%), endometrial polyp (32.2%), hormonal effect (25.7%) and malignancy (7.9%) were diagnosed in the second endometrial sampling.</p> <p><strong>CONCLUSİON</strong></p> <p>The detection of malignancy in 7.9% of patients who underwent repeat sampling after an initial insufficient endometrial pathology result highlights the importance of repeating the procedure, especially in older patients. Additionally, the fact that 40.8% of repeat samplings also resulted in insufficient specimens suggests that alternative methods should be considered for second endometrial samplings.</p> <p> </p> DR. Ramazan ADAN, DR. Doğaç ALTIPARMAK, DR. Sinan SÜRÜCÜ, DR. Teksin İŞGÖRÜCÜ, DR. Fatih ŞAHİN, DR. Veli MİHMANLI Copyright (c) 2025 Journal of Current Medical Research and Opinion https://creativecommons.org/licenses/by/4.0/ http://www.cmro.in/index.php/jcmro/article/view/1088 Fri, 15 Aug 2025 00:00:00 +0000 Prevalence and Antimicrobial-Resistant Patterns of Pseudomonas aruginosa among Burn Patients http://www.cmro.in/index.php/jcmro/article/view/1089 <p>Nosocomial infections are a significant global health issue, posing serious public health challenges in hospitals worldwide. The rise of drug-resistant bacteria causing these infections is increasingly problematic, exacerbated by inadequate hygiene practices and routine antimicrobial use, which contribute to heightened antimicrobial resistance. Pseudomonas aeruginosa is common causes of nosocomial infections. Furthermore, antimicrobial resistance is frequently observed in these pathogens, posing significant challenges to treatment. Pseudomonas aeruginosa is one of the commonest organisms causing different infections like wound infections, Lower Respiratory Tract Infection, Urinary tract infection, infections in burn patient in hospital setting. The increasing trend of antibiotic resistance in Pseudomonas aeruginosa poses a challenge to their empiric treatment with conventional agents. So, the objective of this study was to determine the prevalence and antimicrobial resistance pattern of Pseudomonas aeruginosa isolated from different clinical samples.</p> Zainab Hamid Jassim, Asmaa Taha Yassen, Noor Al-Huda Muthaffar Mahdi, Yasmin Nghemish Mezal, Furgan Ali Hassan, Khaleda Murad Jihad, Afrah Abd AL-Salam Fadl, Afrah Murtada K adhim Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/ http://www.cmro.in/index.php/jcmro/article/view/1089 Fri, 08 Aug 2025 00:00:00 +0000 Using Nanotechnology in Kidney Treatment http://www.cmro.in/index.php/jcmro/article/view/1090 <p>Glomerulonephritis (GN) is a group of inflammatory diseases characterized by glomerular injury and lesions. The causes of GN are relatively complex, and the pathogenesis is not yet clear. It may be caused by autoimmune dysfunction or may be related to multiple factors, such as genetics, infection, drugs, viruses, and the environment. GN can be divided into primary and secondary GN in terms of etiology . Common pathological types of primary GN include acute GN, crescentic GN, membranous GN, membranoproliferative GN, mesangial proliferative GN, focal segmental glomerulosclerosis (FSG), minimal change GN, IgA nephropathy (IgAN) and chronic GN. The most common types of secondary GN include diabetic nephropathy (DN) and lupus nephritis (LN). The symptoms of GN vary widely. Many patients have no special symptoms in the early stage. Some patients present with nephritic syndrome (hematuria, proteinuria, edema and hypertension), and some patients show nephrotic syndrome (hyperlipidemia, severe edema, heavy proteinuria and hypoproteinemia). Even patients with the same pathological characteristics may exhibit varying degrees of proteinuria&nbsp; However, some typical clinical manifestations can correspond to specific GN. After 1–4 weeks of streptococcal infection, patients with symptoms such as edema, hypertension, and hematuria can be diagnosed with acute GN. Recurrent episodic microscopic or macroscopic hematuria is a landmark clinical feature of IgAN, which is the most common primary GN in the world .</p> Tabark Faez Ghanm, Sajjad Maytham Abbas, Aya Fawzi Mutuk, Baneen Ameer Maneam, Salwa Aqeel Khleel Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0/ http://www.cmro.in/index.php/jcmro/article/view/1090 Fri, 08 Aug 2025 00:00:00 +0000